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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PTPRM
All Species:
22.73
Human Site:
Y962
Identified Species:
55.56
UniProt:
P28827
Number Species:
9
Phosphosite Substitution
Charge Score:
-0.11
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P28827
NP_001098714.1
1452
163682
Y962
N
G
N
Y
I
D
G
Y
H
R
P
N
H
Y
I
Chimpanzee
Pan troglodytes
XP_512029
1532
172097
Y1042
N
G
N
Y
I
D
G
Y
H
R
P
N
H
Y
I
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_537326
1352
152839
K893
S
A
P
W
D
S
A
K
K
D
E
N
R
M
K
Cat
Felis silvestris
Mouse
Mus musculus
P28828
1452
163576
Y962
N
G
N
Y
I
D
G
Y
H
R
P
N
H
Y
I
Rat
Rattus norvegicus
Q64604
1898
211475
Y1405
N
A
N
Y
I
D
G
Y
R
K
Q
N
A
Y
I
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512422
1366
153344
G907
N
R
N
K
N
R
Y
G
N
I
I
S
Y
D
H
Chicken
Gallus gallus
Q6YI48
1434
161661
H945
D
G
Y
H
R
S
N
H
F
I
A
T
Q
G
P
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
B3DK56
1444
162642
Y950
N
A
N
Y
I
D
G
Y
H
R
S
N
H
F
I
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P16621
2029
229038
Y1536
N
A
N
Y
C
D
G
Y
R
K
H
N
A
Y
V
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q9BMN8
2200
246601
Y1709
N
A
N
Y
V
D
G
Y
D
K
P
R
S
Y
I
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
93.9
N.A.
85.5
N.A.
97.4
27.1
N.A.
62.1
54.4
N.A.
52.4
N.A.
25.5
N.A.
24.6
N.A.
Protein Similarity:
100
94.2
N.A.
87.5
N.A.
98.6
41.9
N.A.
75.7
72.3
N.A.
69.3
N.A.
40.4
N.A.
38.7
N.A.
P-Site Identity:
100
100
N.A.
6.6
N.A.
100
66.6
N.A.
13.3
6.6
N.A.
80
N.A.
53.3
N.A.
60
N.A.
P-Site Similarity:
100
100
N.A.
20
N.A.
100
73.3
N.A.
33.3
26.6
N.A.
86.6
N.A.
66.6
N.A.
73.3
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
50
0
0
0
0
10
0
0
0
10
0
20
0
0
% A
% Cys:
0
0
0
0
10
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
10
0
0
0
10
70
0
0
10
10
0
0
0
10
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
10
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
10
0
0
0
0
10
0
% F
% Gly:
0
40
0
0
0
0
70
10
0
0
0
0
0
10
0
% G
% His:
0
0
0
10
0
0
0
10
40
0
10
0
40
0
10
% H
% Ile:
0
0
0
0
50
0
0
0
0
20
10
0
0
0
60
% I
% Lys:
0
0
0
10
0
0
0
10
10
30
0
0
0
0
10
% K
% Leu:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
10
0
% M
% Asn:
80
0
80
0
10
0
10
0
10
0
0
70
0
0
0
% N
% Pro:
0
0
10
0
0
0
0
0
0
0
40
0
0
0
10
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
10
0
10
0
0
% Q
% Arg:
0
10
0
0
10
10
0
0
20
40
0
10
10
0
0
% R
% Ser:
10
0
0
0
0
20
0
0
0
0
10
10
10
0
0
% S
% Thr:
0
0
0
0
0
0
0
0
0
0
0
10
0
0
0
% T
% Val:
0
0
0
0
10
0
0
0
0
0
0
0
0
0
10
% V
% Trp:
0
0
0
10
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
10
70
0
0
10
70
0
0
0
0
10
60
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _